Adrenocortical Carcinoma Reference Information

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Mitotane
General Mitotane Info Adjuvant Mitotane Treatment for Adrenocortical Carcinoma Mitotane - Drug Boosts Adrenal Cancer Survival Mitotane Absorption - Chocolate, Emulsion, and Milk Low-Dose Monitored Mitotane Treatment Achieves the Therapeutic Range with Manageable Side Effects in Patients with Adrenocortical Cancer Mitotane and Cholesterol Mitotane increases the radiotherapy inhibitory effect and induces G2-arrest in combined treatment on both H295R and SW13 adrenocortical cell lines Excerpt from Adrenal Insufficiency and Adrenal Crisis
Surgery and Novel Treatments
Combined liver and inferior vena cava resection for adrenocortical carcinoma Adrenocortical carcinoma invading the inferior vena cava: case report and literature review Adrenocortical carcinoma: role of laparoscopic surgery in treatment. UCLA Endocrine Surgery Long-term results of surgical resection of lung metastases. Cancer Ablation Radiofrequency ablation of lung metastases: factors influencing success. Theraspheres Cyberknife Radioembolization Hyperthermia Radioembolization for the treatment of unresectable hepatocellular carcinoma: A clinical review
Interventional Radiation
NIH Radiation Therapy Fact Sheets Intro to Radiation Radiation Treatments New Standards Needed for Radiation Therapy Efficacy of Adjuvant Radiotherapy of the Tumor Bed on Local Recurrence of Adrenocortical Carcinoma Coblation technology — a controlled, non-heat driven process
Anti-Angiogenisis
Harvard Science - Many have 'cancer,' but few progress to true disease Challenges of antiangiogenic cancer therapy: trials and errors, and renewed hope CASE 2. Response in a Patient With Metastatic Adrenal Cortical Carcinoma With Thalidomide Anti-Angiogenic Protocol Copper May Play Role In 'Starving' Cancer To Standstill Copper deficiency as an anti-cancer strategy Natural health products that inhibit angiogenesis: a potential source for investigational new agents to treat cancer—Part 1 Natural health products that inhibit angiogenesis: a potential source for investigational new agents to treat cancer—Part 2 How Angiogenesis Inhibition Improves Chemotherapy Outcomes: An Expert Interview With Dr. Lee Ellis New Anti-angiogenesis Treatment: Combination Therapy Obliterates New Vessel Growth In Tumors And Retinopathy Angioprevention’: angiogenesis is a common and key target for cancer chemopreventive agents A Multitargeted, Metronomic, and Maximum-Tolerated Dose "Chemo-Switch" Regimen is Antiangiogenic, Producing Objective Responses and Survival Benefit in a Mouse Model of Cancer Combination angiostatic therapy completely inhibits ocular and tumor angiogenesis. Fibrous capsule formation around titanium and copper. Thrombospondin 1, a mediator of the antiangiogenic effects of low-dose metronomic chemotherapy Low-dose Metronomic Combined with Intermittent Bolus-dose Cyclophosphamide Is an Effective Long-term Chemotherapy Treatment Strategy Continuous low-dose anti-angiogenic/metronomic chemotherapy: from the research laboratory into the oncology clinic Hypoxic regulation of glucose transport, anaerobic metabolism and angiogenesis in cancer: novel pathways and targets for anticancer therapeutics
Avastin
Treatment Study Using Bevacizumab [AVASTIN] for Patients With Adrenocortical Carcinoma Avastin Package Insert Clinical Trial: Phase I Study of S-1 in Combination with Oxaliplatin and Bevacizumab in Patients with Advanced Solid Tumors Clinical Trial: Bevacizumab and Sunitinib in Treating Patients With Solid Tumors Personalized Cancer Cocktails - Thalidomide & Avastin
EGFR
Brain metastasis in renal cell cancer responding to sunitinib
IGF
Preclinical Targeting of the Type 1 Insulin-like Growth Factor Receptor in Adrenocortical Carcinoma. Expression of insulin-like growth factor-II and its receptor in pediatric and adult adrenocortical tumors. Rosiglitazone Inhibits Adrenocortical Cancer Cell Proliferation by Interfering with the IGF-IR Intracellular Signaling. Preclinical Targeting of the Type 1 Insulin-like Growth Factor Receptor in Adrenocortical Carcinoma.
Treating Cushings Syndrome
Cushings Support and Research Mifepristone (RU 486) in Cushing's syndrome Pharmacological management of Cushing's syndrome: an update Treatment of severe psychosis due to ectopic Cushing's syndrome Metyrapone - General Infoe Metyrapone - Effects of drugs on the adrenal cortex and its tumors The combined use of sodium valproate and metyrapone in the treatment of Cushing's syndrome Short and long-term responses to metyrapone in the medical management of 91 patients with Cushing's syndrome
Low Dose Naltrexone
Low Dose Naltrexone General Info Gazorpa LDN FAQs LDN Yahoo Group Additional LDN Yahoo Group The long-term survival of a patient with pancreatic cancer with metastases to the liver after treatment with the intravenous alpha-lipoic acid/low-dose naltrexone protocol. Methylnaltrexone inhibits opiate and VEGF-induced angiogenesis: role of receptor transactivation. Neuroimmunotherapy of untreatable metastatic solid tumors with subcutaneous low-dose interleukin- 2, melatonin and naltrexone: modulation of interleukin- 2-induced antitumor immunity by blocking the opioid system.
Stem Cells
Generic Search Scientists Weigh Stem Cells’ Role as Cancer Cause
Thalidomide
Mayo Clinic - Thalidomide: Research advances in cancer and other conditions Dramatic Responses to Therapy in Rare Tumors: CASE 2. Response in a Patient With Metastatic Adrenal Cortical Carcinoma With Thalidomide Personalized Cancer Cocktails - Thalidomide & Avastin
Tetrathiomolybdate (TM)
Tetrathiomolybdate - Laboratory Study Explains Clinical Promise Of Anti-Angiogenesis Cancer Drug Tetrathiomolybdate (TM) promotes tumour necrosis and suppresses distant metastases in animal model of head and neck cancer Cancer therapy with tetrathiomolybdate: antiangiogenesis by lowering body copper--a review. Tetrathiomolybdate Inhibits Angiogenesis and Metastasis Through Suppression of the NF{kappa}B Signaling Cascade
New Therapies
University of Pennsylvania Photodynamic Therapy Gamma Knife Surgery Locations Precision Lung Laser Surgery Germany New Treatments for Liver Mets Coblation® technology New Treatment for Spinal Metastases Improves Quality of Life for Some Cancer Patients (dateline June 3, 2007)
DCA-- Dichloroacetate
The DCA Site DCA and Caffeine Warning University of Alberta DCA Research Information DCA May Cause Liver and Kidney Cancer DCA induces apoptosis, decreases proliferation, and inhibits tumor growth, without apparent toxicity.

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